A new flaw has been discovered in IE that could allow an attacker to take control of your computer.
…attackers could exploit it by feeding users malicious code disguised as a Windows help file — such files have a “.hlp” extension — then convincing them to press the F1 key when a pop-up appeared.
Microsoft advises its customers to not press F1 if a website tells them to.
Windows7 users are safe from this exploit.
See more here